Shedding light on the ‘little brain’ of the gut to better understand the neurological
components of gut motility, secretions and gastrointestinal diseases
Related publications
Ochoa-Cortes F, Turco F, Linan-Rico A,
Soghomonyan S, Whitaker E, Wehner S,
Cuomo R, Christofi FL: Enteric glial cells:
A new frontier in neurogastroenterology
and clinical target for inflammatory bowel
diseases. Inflamm Bowel Dis. Dec 2015;
Ren T, Grants I, Alhaj M, McKiernan M,
Jacob- son M, Hassanain HH, Frankel
W, Wunderlich J, Christofi FL: Impact of
disrupting adenosine A3 receptors (A3/
AR) on colonic motility or progression of
colitis in the mouse. Inflamm Bowel Dis.
2011; 17( 8):1698-1713.
Ochoa-Cortes F, Linan-Rico A, Jacobson
KA, Christofi FL: Potential for developing
purinergic drugs for gastrointestinal
diseases. Inflamm Bowel Dis. 2014; 20( 7):
1259-1287.
Linan-Rico A, Wunderlich J, Enneking JT,
Tso DR, Grants I, Williams KC, Otey A, Michel
K, Shemann M, Needleman B, Harzman
A, Christofi FL: Neuropharmacology of
purinergic receptors in human submucous
plexus: Involvement of P2X1, P2X2, P2X3
channels, P2Y and A3 metabotropic
receptors in neurotransmission.
Neuropharmacology. 2015; 95: 83-99.
Gombash SE, Cowley CJ, Fitzgerald JA,
Iyer CC, Fried D, McGovern VL, Williams
KC, Burghes AHM, Christofi FL, Gulbransen
BD, Foust KD: SMN deficiency disrupts
gastrointestinal and enteric nervous system
function in mice. Hum Mol Genet. 2015;
24( 13): 3847-3860.
Fievos Christofi, PhD
